Your veins keep blood circulating throughout your body. Normally, blood flow to your limbs is controlled by one-way valves that help propel your blood back to your heart. Sometimes these valves stop functioning, allowing blood to pool in the legs, which can progress to a condition called chronic venous insufficiency (CVI). If not treated, CVI often causes lymphedema, which leads to swelling and skin changes.
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Study pathway. CVD: chronic venous disease.